Researchers implanted a genetically engineered pig liver into a human patient and demonstrated the graft could support key liver functions for an extended period before complications required its removal. The patient later died, but investigators say the operation proved feasibility for xenotransplantation and highlighted remaining immunologic and perioperative challenges. The team reported the case as a milestone that confirms multi-gene editing can reduce immediate graft rejection and sustain metabolism and synthetic function in a human host. Sources and institutional affiliations were not specified in the item, but the finding was presented as a step toward addressing organ shortages while underscoring the complexity of translating xenografts into routine clinical care. Clinicians and researchers told attendees and colleagues that follow-up work must focus on longer-term immunomodulation, infection control, and manufacturing standards for donor animals to move from single-case demonstrations to regulated clinical trials.