Researchers implanted a genetically modified pig liver into a human and showed the graft could support core liver functions for an extended period before complications forced removal. The procedure proved that a porcine organ can perform essential metabolic and synthetic tasks in a human host, offering a proof‑of‑concept for xenotransplantation. Investigators reported the implant supported key liver processes but the patient later died after complications unrelated to immediate graft function. The team and external experts highlighted both the potential to address organ shortages and the complex immunologic and infectious risks that remain. Xenotransplantation is the transplantation of organs between species and requires multiple genetic edits in donor animals to reduce rejection and viral risk.