Parse Biosciences and Codebreaker Labs announced a collaboration to combine engineered variant libraries with Parse’s single‑cell transcriptomics to experimentally measure how genetic variants affect cellular transcriptomes. The partners aim to generate functional, single‑cell resolution datasets that can inform variant interpretation, target discovery and AI model training for drug discovery. The initiative builds on Parse’s recent commitments to large single‑cell perturbation datasets and the company’s pending acquisition by Qiagen, offering a path to scale variant‑to‑phenotype mapping for therapeutic validation.