New research advances Parkinson’s disease (PD) diagnosis and management. Synthetic MRI techniques differentiate motor subtypes by analyzing brain volume and myelin alterations. Wearable technologies improve medication adjustment accuracy over traditional methods, enabling personalized care. A novel association between anxiety disorders, anxiolytic use, and increased PD risk was identified, expanding understanding of neurodegenerative disease etiology. These studies offer enhanced clinical tools and insights into PD pathophysiology.