Researchers published PanMAN (Pangenome Mutation-Annotated Network), an evolutionary compression data structure that encodes phylogenies, mutations and whole-genome alignments to dramatically cut storage needs for pangenomic datasets. The method stores a root reference and annotates variations along a phylogenetic tree, reducing redundant storage while preserving biologically relevant mutation and alignment information. Clarification: Pangenomics analyzes many genomes from a species to capture population variation beyond a single reference. PanMAN aims to lower storage and computational costs in large-scale genomic surveillance and population studies, enabling faster phylogenetic updates and broader access to population-level references.