Organ transplantation continues to progress with new preservation and evaluation techniques. Normothermic machine perfusion enhances liver graft viability from circulatory death donors, improving transplant outcomes. Digital and robotic-assisted technologies are enabling precision in ACL reconstruction. Uniform guidelines for pre-transplant kidney biopsy interpretation aim to increase diagnostic consistency. Additionally, regulatory T cell and virus-specific T cell therapies are revolutionizing post-transplant immune management, reducing rejection and improving graft survival.