Researchers reported progress on an eye preservation device—Eye-in-a-Care-Box (ECaBox)—designed to maintain freshly removed eyeballs using oxygen-rich perfusion via the eye’s artery. In experiments using pig eyes, the treated eyes showed higher viability after 24 hours than eyes kept outside the device at room temperature, and the perfused tissue appeared capable of responding to light, suggesting preserved functional signaling potential. The device is designed with sealed temperature and pressure control and a clear window for imaging while perfused, aiming to slow degeneration that occurs shortly after eye removal. The work, discussed by collaborators including Pia Cosma at the Centre for Genomic Regulation, strengthens the translational path for retina and whole-eye preservation, which is a major barrier to expanding eye transplant feasibility.