Preclinical mouse data suggest cold plasma-activated water may inhibit breast cancer tumor growth. Researchers reported in a study on cold plasma-activated water’s effects against MCF7 breast cancer tumors, presenting results consistent with an anti-tumor activity profile. The approach is notable because cold plasma-activated water is positioned as a minimally invasive, non-traditional therapeutic modality rather than a systemic drug. Further work will be needed to define dosing parameters, mechanisms of action, and translational feasibility for breast cancer subtypes beyond the tested model.