Cutting-edge developments advance infectious disease prevention and treatment. A universal coronavirus vaccine design focuses on conserved T-cell epitope regions enhancing cross-reactive immunity, published by La Jolla Institute. Additionally, a rapid, extraction-free HPV DNA test utilizing LAMP technology emerges for low-resource settings in Mozambique. A CRISPR-based tuberculosis diagnostic has been developed for sputum samples, ideal for constrained environments. Vaccine candidates targeting multidrug-resistant Acinetobacter baumannii and Nipah virus therapies highlight further progress in infectious disease control.