Researchers have developed an instantaneous brain-to-voice neuroprosthesis allowing a man with amyotrophic lateral sclerosis (ALS) to communicate using synthesized speech reproducing his own voice’s tone and intonation. The implanted device records neural activity from 256 electrodes in speech motor regions and uses AI algorithms to decode speech in real time, surpassing prior models limited to text output or delayed speech. This breakthrough offers new hope for restoring eloquent, expressive speech in people with paralysis from neurological diseases.