Innovations in cancer detection are progressing with novel noninvasive tests leveraging gene methylation patterns. A method utilizing automatically processed bilateral nasal swabs can detect nasopharyngeal carcinoma through DNA methylation biomarkers, as published in BMC Cancer. Similarly, studies on serum LDH levels reveal a U-shaped curve predicting patient mortality across various cancers, highlighting metabolic enzymes' prognostic potential. These advances represent promising strides toward accessible early detection and prognostication in oncology.