Researchers at Hebrew University and Believer Meats reported a Nature paper describing a non‑genetic method to induce stable, long‑term self‑renewal in bovine cells by activating telomerase and PGC1α. The technique achieves cellular immortalization without transgenic modification, addressing a major technical and regulatory bottleneck for cultivated meat production. Authors demonstrated that activating telomerase and mitochondrial biogenesis factors allowed bovine cells to bypass senescence while maintaining normal karyotype and differentiation capacity. The approach mirrors prior work in poultry and suggests a path to create safe, stable, and scalable cell lines for cultured beef and lamb. If reproduced and accepted by regulators, non‑GM immortalization could lower costs and simplify approval pathways for cultivated meat companies, accelerating commercialization and industrial‑scale manufacturing.
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