Over 300 current and former NIH employees have signed the Bethesda Declaration, a formal letter addressed to NIH Director Jay Bhattacharya, criticizing recent grant cancellations, funding freezes, and political interference in scientific research. The declaration highlights adverse impacts on research areas including health disparities, immunization, and global collaboration. The signatories urge restoration of research support, peer review integrity, and stopping politicization of science funding, signaling a critical moment of dissent within the biomedical research community.