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Pleno launches early access for multiomics biomarker detection platform
San Diego-based Pleno has initiated an early-access program for its Raptor platform, which leverages 'hypercoding' technology with circularizable probes to simultaneously target tens of thousands...
UCLA develops off-the-shelf CAR-NKT immunotherapy for metastatic kidney cancer
UCLA researchers have engineered AlloCAR70-NKT, a novel allogeneic cell therapy harnessing genetically modified invariant natural killer T cells, to combat metastatic renal cell carcinoma...
Biogen and Eisai earn FDA nod for subcutaneous Leqembi Alzheimer’s drug
The FDA has approved a subcutaneous formulation of Eisai and Biogen’s Alzheimer's therapy Leqembi, facilitating easier administration that could enhance patient adherence compared to the...
Groundbreaking pig-to-human lung transplant sustains graft nine days
A Chinese research team at Guangzhou Medical University achieved the first pig lung transplantation into a human body, maintaining graft viability for nine days. Using CRISPR gene-editing to...
Breakthrough AI method enhances early cancer detection reliability
Johns Hopkins University scientists have developed Multidimensional Informed Generalized Hypothesis Testing (MIGHT), an AI-based framework that optimizes cancer screening tests by balancing high...
Salk Institute discovers critical microprotein supporting mitochondrial health
Researchers at the Salk Institute have identified a novel microprotein, SLC35A4-MP, essential for maintaining mitochondrial structure and regulating metabolic stress in mouse adipose tissue. This...
FDA approves Sanofi's BTK inhibitor rilzabrutinib for immune thrombocytopenia
The FDA granted approval to Sanofi's BTK inhibitor rilzabrutinib, acquired through its $3.7 billion Principia Biopharma buyout, for the treatment of immune thrombocytopenia. This marks a...
Cytokinetics Advances Heart Muscle Disorder Therapy
Cytokinetics reported positive late-stage clinical trial results for aficamten, a cardiac myosin inhibitor, showing improved exercise capacity in patients with obstructive hypertrophic...
FDA Approval and Challenges in Alzheimer's Disease Drugs
The FDA has approved a new subcutaneous formulation of Eisai and Biogen's Alzheimer’s drug Leqembi, marking an incremental step in the effort to compete with existing treatments like Eli Lilly's...
Biopharma Financing Highlights August 2025
The biopharmaceutical sector continues to attract significant investment activity in 2025. Notable financings in August include Patient Square Capital raising over $3 billion for its healthcare...
AI and Machine Learning Drive Advances in Biomedicine
Artificial intelligence continues to transform biomedicine, from enhancing early cancer detection to enabling complex multiomics analyses. Johns Hopkins researchers introduced MIGHT, a machine...
Breakthroughs in Organ Transplantation and Preservation
Significant advancements in organ transplantation are emerging with the integration of new technologies and methodologies. Normothermic regional perfusion (NRP) is revolutionizing liver...
Cancer Therapy Innovations and Molecular Discoveries
Recent studies have uncovered novel molecular drivers and therapeutic targets in various cancers. A CX26 protein stabilizing c-Myc has been linked to pancreatic cancer progression. Additionally,...
Gut-Brain Axis Research Illuminates Alzheimer's Pathology
Emerging evidence delineates critical immune interactions within the gut-brain axis relevant to Alzheimer’s disease (AD). Research from the Buck Institute using 5XFAD mouse models reveals...
Advancements in Biomedical Engineering Education and Tools
Innovative educational approaches and technologies are enhancing biomedical engineering training. The introduction of the CellSpark simulation platform aids understanding of electrophysiology for...
Biotech Industry Moves and Regulatory Updates
The biotech and pharmaceutical sectors have witnessed significant leadership transitions, collaborations, and regulatory decisions in August 2025. Sanofi appointed Marcia Kayath as Chief Medical...
CDC Leadership Turmoil Signals National Biosecurity Risks
The Centers for Disease Control and Prevention (CDC) is facing a leadership crisis after the dismissal of Director Susan Monarez, alongside multiple high-level resignations. This upheaval stems...
Novo Nordisk Partners with Replicate for RNA-Based Metabolic Therapies
Novo Nordisk has initiated a multi-year collaboration with Replicate Bioscience to develop novel cardiometabolic treatments using Replicate's self-replicating RNA (srRNA) platform. With potential...
AI and Machine Learning Propel Advances in Biomedicine and Drug Discovery
Significant progress has been made in applying artificial intelligence and machine learning across biomedical domains. Notable developments include Raina Biosciences’ GEMORNA platform using...
Breakthrough in Transplantation: Normothermic Machine Perfusion and Organ Utilization
Innovations in organ transplantation focus on improving graft viability and utilization. Recent research highlights normothermic machine perfusion techniques enhancing liver preservation from...