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Sarepta Gene Therapy Death Spurs Investor Selloff
Sarepta Therapeutics experienced a 36% stock drop after disclosure of a third patient death linked to its gene therapies this year. The latest fatality involved a 51-year-old treated with SRP-9004...
Engineered E. coli Produces Milk Proteins for Vegan Dairy
Scientists have genetically modified E. coli bacteria to synthesize key proteins found in milk, creating potential for producing vegan cheese and yogurt without animal-derived ingredients. This...
Novel Click Chemistry Used Safely for Cancer Treatment in Humans
Researchers have successfully applied Nobel Prize-winning click chemistry technology for the first time in humans, enabling targeted delivery of chemotherapy drugs directly to tumors. This method...
PathoPlex Multiplexing Transforms Kidney Disease Mapping
A new high-dimensional multiplexing technology named PathoPlex offers unprecedented insight into immune-mediated kidney diseases by allowing spatially resolved cellular and molecular mapping. This...
Single-Cell Atlas Reveals Chemokine Links in Type 2 Diabetes
A groundbreaking single-cell study has unveiled crucial immunological disruptions in type 2 diabetes, linking specific chemokines to disease progression. By dissecting immune cell populations and...
Xeltis Reports Positive EU Clinical Data for Coronary Bypass Conduit
Xeltis has announced encouraging results from a European clinical trial evaluating Xabg, an artificial coronary artery bypass conduit that gradually transitions to living tissue through...
Solid Oxide Cells Advance with Monolithic Gyroidal 3D Printing
Researchers have introduced a novel 3D-printed monolithic gyroidal design for solid oxide cells, significantly enhancing their efficiency, durability, and structural integration. Moving beyond...
Machine Learning Deciphers Sorghum Mold Resistance Genetics
Applying machine learning techniques, scientists have unraveled the complex genetic basis for mold resistance in sorghum, a key cereal crop. This approach accelerates identification of resistance...
FDA Approval Process Under Scrutiny Amid Mifepristone Report Debate
A recent report challenging the FDA's approval of mifepristone has ignited controversy, though the medication remains one of the most extensively reviewed and safely used drugs over 25 years....
Sarepta Gene Therapy Deaths Spike: Stock Tumbles 36%
Sarepta Therapeutics faces a crisis after the death of a third patient linked to its gene therapies this year. The latest fatality involved a 51-year-old man with limb girdle muscular dystrophy...
Gene Therapy Safety Crisis Sparks Industry Reckoning
The recent fatalities linked to Sarepta’s gene therapies evoke parallels with the historic Jesse Gelsinger case, reigniting scrutiny of safety in AAV-mediated treatments. Industry experts and FDA...
Patient Voices Urge Duchenne Therapeutics Progress Despite Risks
Mothers of Duchenne muscular dystrophy patients provide poignant testimony amid escalating fatalities linked to gene therapies. They underscore the harsh realities faced by families confronting a...
Advanced Multiplexing Maps Kidney Immune Disease with Precision
Researchers have introduced PathoPlex, a novel multiplexing imaging platform that enables high-dimensional, spatially-resolved analysis of immune-mediated kidney diseases. This breakthrough...
Single-Cell Atlas Illuminates Immune Drivers in Type 2 Diabetes
A pioneering single-cell atlas study has identified key chemokines linked to immune dysfunction in type 2 diabetes, shedding light on its complex pathophysiology beyond metabolic factors. The...
Engineered Bacteria Usher New Era in Animal-Free Dairy Proteins
Scientists have successfully bioengineered Escherichia coli to produce authentic milk proteins vital for cheese and yogurt manufacture without animal inputs. This innovation paves the way for...
Additive Manufacturing Innovates Solid Oxide Cell Design
Researchers unveiled a novel additive manufacturing approach to produce monolithic gyroidal solid oxide cells (SOCs) that significantly improve efficiency and durability. This three-dimensional...
Machine Learning Deciphers Sorghum’s Genetic Mold Resistance
Advanced machine learning techniques have deciphered the complex genetic basis underlying sorghum’s resistance to grain mold, a significant fungal threat to this key cereal crop. This integrative...
Xeltis Reports Positive Clinical Results for Bioengineered Heart Conduit
Xeltis announced favorable outcomes from its EU clinical trial evaluating Xabg, an innovative coronary artery bypass graft made from bioresorbable materials that regenerate into living tissue....
HHS Notice on Federal Benefits Provokes Legal Pushback
A new HHS federal notice restricting benefit access for undocumented and lawfully present immigrants has triggered criticism from advocacy groups and legal challenges. Democratic attorneys general...
Sarepta Gene Therapy Crisis: FDA Moves to Halt Duchenne Treatment
Sarepta Therapeutics is facing a major regulatory challenge as the FDA prepares to request a halt on shipments of its Elevidys gene therapy for Duchenne muscular dystrophy following multiple...