Get the Daily Brief

All action, no filler. BioBriefs delivers biotech’s 10 must-know updates, every morning.

Latest Biotech News

New Therapies and Data in EGFR-Mutant Lung Cancer: Combination Approaches Extend Survival

September 08, 2025

Clinical trials presented at WCLC 2025 demonstrate advances in EGFR-mutated NSCLC management through combinatory strategies. Tagrisso (osimertinib) combined with chemotherapy reduced death risk by...

Draig Therapeutics Raises $140M to Advance Non-Dissociative Oral Neuropsychiatric Drugs

September 08, 2025

Draig Therapeutics, a clinical-stage neuropsychiatry company co-founded by Cardiff University scientists, secured $140 million in Series A funding led by Access Biotechnology. The company focuses...

Rapport Therapeutics’ Seizure Drug Hits Mid-Stage Endpoints, Shares Surge

September 08, 2025

Rapport Therapeutics announced positive topline results from a Phase 2a trial of its focal onset seizure medication RAP-219, achieving the primary endpoint by significantly reducing long seizure...

NRG Therapeutics Secures $67M to Develop Mitochondrial Drug for Parkinson’s and ALS

September 08, 2025

NRG Therapeutics has raised $67 million in financing from investors including the venture arms of Merck KGaA and Novartis to advance its mitochondrial-targeted drug aimed at neurodegenerative...

AI Advances Aid Early Detection of Rare Cardiac Amyloidosis

September 08, 2025

Pfizer is supporting global initiatives deploying artificial intelligence (AI) to enhance early identification of transthyretin cardiac amyloidosis (ATTR-CM), a rare and underdiagnosed cause of...

Sneha Goenka Honored for Ultrafast Genome Sequencing Impacting Critical Pediatric Diagnosis

September 08, 2025

MIT Technology Review’s 2025 Innovator of the Year, Sneha Goenka, has advanced ultrafast genome sequencing technology that delivers genetic diagnoses in under eight hours, a dramatic acceleration...

Junshi Biosciences Advances IL-17 Psoriasis Drug with Phase 3 Win Set for China Approval

September 08, 2025

Junshi Biosciences announced positive Phase 3 results for its anti-IL-17A monoclonal antibody JS005 in treating moderate-to-severe plaque psoriasis among Chinese patients, achieving primary and...

Fentanyl-Hunter: AI Platform Enhances Detection of Opioid Metabolites for Toxicology

September 08, 2025

A multidisciplinary research team developed Fentanyl-Hunter, a machine learning-driven platform for comprehensive screening of fentanyl compounds and their metabolites in biological and...

Lung Cancer: Novel Therapeutics Disrupt Treatment Paradigms

September 08, 2025

Recent landmark studies presented at the International Association for the Study of Lung Cancer (IASLC) 2025 World Conference have revealed transformative advances in lung cancer therapy....

Small Cell Lung Cancer: Antibody-Drug Conjugates and Chemoradiotherapy Updates

September 08, 2025

Advancements in small cell lung cancer (SCLC) management were spotlighted at IASLC 2025, with novel therapeutic options gaining traction. The first-in-human Phase 1 trial of DLL3-targeting ADC...

Durvalumab and Nivolumab Trials: Evolving Immunotherapy Roles in Lung Cancer

September 08, 2025

Immunotherapy advancements continue to refine lung cancer treatment paradigms. The Phase 3 EA5181 trial demonstrated no overall survival benefit from concurrent plus consolidative durvalumab...

AI and Digital Innovation Transforming Disease Detection and Clinical Trials

September 08, 2025

Artificial intelligence (AI) and digital technologies are rapidly reshaping medical diagnostics and clinical trial execution. Pfizer-led initiatives employing AI algorithms are accelerating early...

Biomarker Strategies and Precision Oncology in Drug Development

September 08, 2025

Precision oncology research increasingly hinges on integrated biomarker testing to refine targeted and immunotherapy development. Labcorp's comprehensive biomarker profiling platforms offer...

Epigenetic and CRISPR Innovations in Therapeutic Development

September 08, 2025

Recent fundraising milestones and clinical advances highlight the growing prominence of epigenetic and gene editing therapies in biotech. China-based Epigenic Therapeutics secured $60 million in...

Neuroscience Renaissance: Neuropsychiatry Startups and Innovations

September 08, 2025

Neuroscience is experiencing a resurgence in biopharmaceutical investment, exemplified by Draig Therapeutics' $140 million Series A financing led by Access Biotechnology and other investors....

Oncology Antibody-Drug Conjugates and Targeted Therapies Progress

September 08, 2025

Development of antibody-drug conjugates (ADCs) continues to gain momentum across oncology indications. Junshi Biosciences reported successful Phase 3 results for JS005, an IL-17A monoclonal...

Opioid Use and Pain Management Post-Cancer Surgery

September 08, 2025

An observational study focusing on U.S. Veterans revealed a concerning trend of long-term opioid prescriptions among patients initially opioid-naïve before curative-intent cancer surgery. These...

Microbiomes in Cancer and Human Health

September 08, 2025

Emerging research explores the intricate role of human microbiomes in tumorigenesis and systemic health. A recent Medical Oncology study implicated microbiome alterations as contributors to...

Chemo-Immunotherapy Cuts Recurrence Risk in Early-Stage NSCLC: NADIM ADJUVANT Trial

September 08, 2025

Interim results from the NADIM ADJUVANT Phase III clinical trial, led by the Spanish Lung Cancer Group (GECP), demonstrate that adjuvant chemo-immunotherapy significantly reduces disease...

AI Advances Early Detection of Cardiac Amyloidosis: Pfizer's Global Initiatives

September 08, 2025

Pfizer is pioneering AI-driven efforts to enhance early detection of transthyretin cardiac amyloidosis (ATTR-CM), a rare and progressive heart failure cause. Across partnerships in the US,...