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1000 Genomes Project Enriched by Long-Read Sequencing Collaborations
The 1000 Genomes Project Long-Read Sequencing Consortium expanded its scope by integrating PacBio data alongside Oxford Nanopore sequencing, aiming to sequence the entire 1000 Genomes cohort with...
Sarepta Therapeutics Faces FDA Demands Amid Gene Therapy Crisis
Sarepta Therapeutics is under intense regulatory scrutiny as the FDA halted shipments of its Duchenne muscular dystrophy gene therapy Elevidys in several countries and called for new studies to...
Thermo Fisher Beats Q2 Estimates, Raises 2025 Guidance
Thermo Fisher Scientific reported better-than-expected Q2 revenue and earnings, with a 3% sales increase year-over-year to $10.86 billion. Life sciences solutions and laboratory products segments...
Malaria Blocked by CRISPR-Edited Mosquito Gene Variant
Scientists have engineered a CRISPR-Cas9 gene editing system that modifies a single amino acid in the mosquito FREP1 gene, rendering mosquitoes unable to transmit malaria parasites. Unlike...
LEO Pharma’s Anzupgo Gains FDA Approval for Chronic Hand Eczema
LEO Pharma’s topical JAK inhibitor cream Anzupgo (delgocitinib) became the first FDA-approved therapy specifically for chronic hand eczema in the U.S. Indicated for moderate to severe cases not...
FDA Launches Fast Track Program for U.S. Drug Onshoring and Affordability
The FDA opened applications for its Commissioner’s National Priority Voucher pilot program offering expedited review timelines of 1-2 months for medicines addressing key U.S. priorities....
AI-Driven Protein Design Enhances Cancer Immunotherapy
Researchers led by Nobel Laureate David Baker have leveraged artificial intelligence to design highly specific protein binders targeting peptides presented by major histocompatibility complex...
1000 Genomes Project Expands Long-Read Sequencing Data with Multiplatform Consortium
The 1000 Genomes Project Long-Read Sequencing Consortium, led by University of Washington researchers, has expanded its dataset by adding Pacific Biosciences (PacBio) long-read sequencing...
Dispatch Bio Launches with $216M for Universal Solid Tumor Immunotherapy
Dispatch Bio has officially launched with $216 million in funding, backing an immunotherapy platform designed to treat diverse solid tumors. The company’s approach involves delivering a viral...
Sarepta Therapeutics Faces Covid Safety and Market Challenges With Duchenne Gene Therapy
Sarepta Therapeutics is grappling with regulatory and safety issues surrounding Elevidys, its gene therapy for Duchenne muscular dystrophy (DMD). The FDA requested a market withdrawal due to...
Abivax’s Ulcerative Colitis Drug Delivers Positive Phase 3 Data, Stock Surges
French biotech Abivax reported positive results from two Phase 3 trials of obefazimod, an oral microRNA-124 enhancer for moderately to severely active ulcerative colitis patients. The 50 mg dose...
Roche’s Diagnostics Division Faces China Pricing Reforms, Reports Flat Revenues
Roche Diagnostics reported a 3% revenue decline in the first half of 2025, mainly driven by volume-based procurement and healthcare pricing reforms in China, which caused a 26% sales drop there....
AstraZeneca’s Gefurulimab Shows Positive Phase 3 Results in Myasthenia Gravis
AstraZeneca announced positive “high-level” results from a global Phase 3 study of gefurulimab, a once-weekly, self-administered complement C5 inhibitor, in adults with generalized myasthenia...
Malaria Transmission Halted by Single Amino Acid CRISPR Edit in Mosquitoes
A novel genetic strategy using CRISPR-Cas9 to edit a single amino acid in the mosquito FREP1 gene confers resistance to malaria parasite transmission. Rather than eliminating mosquitoes or...
Thermo Fisher Scientific Beats Earnings, Raises 2025 Guidance on Cost Cuts and Growth
Thermo Fisher Scientific reported a strong Q2 2025 performance, with revenues up 3% year-over-year to $10.86 billion, beating analyst estimates. The life sciences solutions segment grew 6%, while...
FDA Introduces National Priority Voucher Program to Accelerate Review for Onshoring and Affordability
The FDA has launched the Commissioner’s National Priority Voucher (CNPV) pilot program to grant accelerated review times of one to two months for new drugs aligning with U.S. national health...
FDA Greenlights Streamlined Stool Kit for Colorectal Cancer Screening
Geneoscopy secured FDA approval for an updated stool collection kit for its RNA-based ColoSense colorectal cancer screening test. The new streamlined kit eliminates the need for patients to...
Expanded Long-Read Sequencing Sheds New Light on Human Genome Variation
Two international research efforts, including the University of Washington-led 1KGP-LRS Consortium and collaborators from PacBio and Johns Hopkins University, have advanced long-read sequencing of...
Targeted RNA Sequencing Emerges as Effective Standalone Oncology Diagnostic
A recent Nature Medicine study from researchers at the University of Toronto and the Hospital for Sick Children demonstrated targeted RNA sequencing performs on par with DNA-based diagnostics in...
Sarepta Therapeutics Faces Clinical and Market Challenges Over Gene Therapy
Sarepta Therapeutics' gene therapy Elevidys for Duchenne muscular dystrophy is currently halted at FDA request amid safety concerns linked to patient deaths. Families and clinicians are grappling...