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New Cancer Therapeutics Emerge from Gene Regulation Research
University of Geneva researchers identified two key proteins involved in the chromatin remodeling process that regulates gene accessibility, which is crucial for controlled gene expression....
Revolution Medicines Secures $2 Billion Deal to Fund RAS Inhibitor Development
Revolution Medicines finalized a major financing agreement with Royalty Pharma, obtaining up to $2 billion in committed capital to support late-stage development and commercialization of its...
Advances in Brain Cancer Therapy Using Fusion Cytokine Technology
Researchers at Virginia Commonwealth University’s Massey Cancer Center and the Institute of Molecular Medicine designed a fusion superkine molecule combining interleukin-24S with interleukin-15,...
Revolution Medicines Secures $2 Billion Deal With Royalty Pharma To Extend RAS(ON) Cancer Drug Funding
Revolution Medicines has signed a landmark $2 billion royalty and debt financing deal with Royalty Pharma to support its RAS(ON) inhibitors, including the leading candidate daraxonrasib. This...
FDA Approves AstraZeneca and Daiichi Sankyo’s Datroway for Lung Cancer Indication
The FDA has expanded AstraZeneca and Daiichi Sankyo’s antibody-drug conjugate Datroway to include treatment for locally advanced or metastatic epidermal growth factor receptor mutated non-small...
Cidara Therapeutics’ Antiviral Shows Strong Phase IIb Results for Flu Prevention
Cidara Therapeutics announced positive Phase IIb trial results for its long-acting antiviral biologic CD-388, demonstrating substantial prevention efficacy against seasonal influenza in healthy,...
Nuvalent Advances Lung Cancer Pipeline with Promising ROS1 Drug and Plans FDA Filing
Nuvalent has revealed compelling phase 1/2 clinical results for its ROS1 inhibitor zidesamtinib, targeting ROS1-positive non-small cell lung cancer patients who failed prior therapies. The drug...
Illumina Expands Multiomics Reach with $425 Million Acquisition of SomaLogic
Illumina has entered into a definitive agreement to acquire proteomics leader SomaLogic from Standard BioTools for up to $425 million, strengthening its multiomics strategy. The purchase includes...
Novo Nordisk Ends Marketing Deal with Hims Over Obesity Drug Compounding Practices
Novo Nordisk has terminated a marketing partnership with telehealth company Hims & Hers Health after only eight weeks, alleging unlawful mass distribution of compounded versions of the obesity...
New AI Tool Deciphers Tumor Cell Diversity for Customized Cancer Treatment
A multinational research collaboration led by the Garvan Institute has introduced AAnet, an AI-based neural network designed to analyze single-cell gene expression profiles from tumors, revealing...
UK Government Unveils Strategy to Become Top Three Life Sciences Hub by 2035
The UK government has introduced a Modern Industrial Strategy focusing on boosting the life sciences sector to rank as Europe’s leader by 2030 and among the top three globally by 2035. Key...
Chromosomal Instability Biomarkers Predicting Chemotherapy Resistance in Cancer Treatment
A collaborative study led by the Spanish National Cancer Research Centre and the University of Cambridge has developed genomic biomarkers based on chromosomal instability (CIN) signatures to...
Nektar Therapeutics Surges on Positive Phase 2b Rezpeg Data in Atopic Dermatitis
Nektar Therapeutics reported encouraging Phase 2b data for rezpegaldesleukin (rezpeg), an immune-modulating agent showing statistically significant improvement in skin clearance for patients with...
Cidara's Flu Vaccine Breakthrough Boosts Stock Surge
Cidara Therapeutics reported positive top-line Phase 2b results for its long-acting antiviral biologic CD-388, demonstrating significant efficacy in preventing seasonal influenza in healthy,...
FDA Leadership Turmoil Marks Agency Shift
The U.S. Food and Drug Administration is experiencing significant leadership upheaval, highlighted by the announced retirement of Jacqueline Corrigan-Curay, acting head of the Center for Drug...
Illumina Expands Proteomics Business with SomaLogic Acquisition
Illumina has agreed to acquire SomaLogic from Standard BioTools in a deal worth up to $425 million, aiming to bolster its multiomics strategy and proteomics capabilities. This acquisition...
Novel Cancer Therapies Show Clinical Progress and Partnerships
Several innovative cancer therapies and strategic partnerships emerged as focal developments. Roche reported promising Phase 3 trial results combining bispecific and antibody-drug conjugate...
Breakthroughs in Diabetes and Obesity Treatments
Noteworthy advances in diabetes and obesity therapies include Amgen’s adjustment of dosing schedules for its obesity drug MariTide following Phase 2 data showing significant weight loss but high...
Chromosomal Instability Biomarkers Predict Chemotherapy Resistance
Researchers at the Spanish National Cancer Research Centre and collaborators developed genomic tests harnessing chromosomal instability (CIN) signatures to predict patient resistance to multiple...
Advances in Medical Imaging: Novel PET Tracers Enhance Cancer Detection
Innovations in molecular imaging have emerged with development of novel PET tracers enhancing cancer diagnosis. Shandong Cancer Hospital introduced a peptide-based tracer outperforming ^18F-FDG in...