Get the Daily Brief
Latest Biotech News
E. coli Turns Plastic Waste Into Common Painkiller
Researchers at the University of Edinburgh have engineered Escherichia coli bacteria to convert polyethylene terephthalate (PET) plastic waste into paracetamol. Combining chemical degradation of...
Thermo Fisher-Tufts Link CDMO and CRO for Faster Cancer Drugs
A white paper by the Tufts Center for the Study of Drug Development, commissioned by Thermo Fisher Scientific, finds that integrating contract development and manufacturing organizations (CDMOs)...
BioCryst Sells European Rights to Rare Disease Drug
BioCryst Pharmaceuticals has divested the European rights to its hereditary angioedema treatment Orladeyo to Italy-based Neopharmed Gentili in a $250 million transaction. The deal marks Neopharmed...
Alphabet-Calico and Mabwell Ink $596M Anti-Aging Antibody Deal
Calico Life Sciences, Alphabet’s longevity-focused biotech, has secured exclusive rights outside China to Mabwell Bioscience's IL-11 targeting monoclonal antibody, 9MW3811, through a deal valued...
FDA Faces Rare Disease Drug Review Challenges
BioCentury reports the FDA is conducting landmark reviews of several rare disease drug approvals, testing its commitment to biomarker-based accelerated approval pathways for orphan drugs....
Study Links Antenatal Inflammation to Later Pulmonary Hypertension
A pivotal study published in Pediatric Research reveals that antenatal inflammation contributes to the development of late pulmonary hypertension in bronchopulmonary dysplasia models. This...
UMass Chan Unveils Mechanism Driving Cilia Development Disorders
Researchers at UMass Chan Medical School have elucidated the role of the TMEM67 protein in ciliopathies, a class of genetic disorders affecting cellular antennae function. Their work, spearheaded...
Parkinson’s Motor Function Boosted by Physical Activity
A pilot study published in npj Parkinson’s Disease indicates that increased physical activity improves motor function in patients suffering from Parkinson’s disease. The findings provide clinical...
Danaher Appoints Stumpe as New Chief Technology Officer
Danaher has named Stumpe, formerly at Tempus and Google, as its new Chief Technology Officer. This strategic hire aims to leverage Stumpe’s extensive tech leadership experience to drive innovation...
New Carbon Economy Consortium Meets to Accelerate Carbon Removal
The New Carbon Economy Consortium (NCEC) gathered at the University of Exeter to coordinate global carbon capture efforts. The consortium focuses on advancing technological, policy, and economic...
FDA Overhauls CAR-T Therapy Regulations to Expand Access
The FDA has removed a safety monitoring requirement imposed on CAR-T cell therapies since their 2017 launch, affirming these treatments can be administered safely without the additional oversight....
Calico Secures $596M Deal for Mabwell’s Anti-Aging Therapeutic
Alphabet’s Calico Life Sciences has entered a licensing agreement with China-based Mabwell Bioscience valued up to $571 million, acquiring rights to a clinical-stage monoclonal antibody targeting...
Breakthrough Molecular Insights Reshape Leukemia Treatment Strategies
A study published in Nature Cancer has revealed that the developmental stage of B cells at leukemia onset critically affects therapy response in pediatric B-cell acute lymphoblastic leukemia...
Vetter Invests $285M in New Clinical Manufacturing Site in Illinois
German contract development and manufacturing organization Vetter has commenced construction of a 160,000-square-foot clinical manufacturing facility in Des Plaines, Illinois, marking a strategic...
UMass Chan Study Deciphers Molecular Basis of Ciliopathies
Researchers at UMass Chan Medical School have elucidated critical molecular mechanisms governing cilia development, shedding light on severe human ciliopathies caused by defects in the TMEM67...
ColdBrew Algorithm Enhances Drug Discovery via Water Dynamics Modeling
Scientists at St. Jude Children’s Research Hospital developed ColdBrew, an innovative computational algorithm that accurately models water molecule positioning in protein binding sites at...
Wholomics Advances Multi-Cancer Detection with Metabolomic Profiling
Startup Wholomics, originating from Dana Farber and University College London collaborations, has presented early data showcasing a novel metabolomic platform for multi-cancer detection in serum...
Neurological Insights Link SLC13A5 Mutations to Severe Epileptic Encephalopathy
Groundbreaking work from the CeMM Research Center has decoded how mutations in the SLC13A5 citrate transporter disrupt neuronal metabolism, causing developmental epileptic encephalopathy (DEE)....
Pesticide Impact on Gut Microbiome Revealed in High-Resolution Study
Researchers at The Ohio State University have published a detailed molecular atlas describing how widespread pesticides affect human gut bacterial species and their metabolism. Exposing...
New Urine-Based Tumor DNA Test Forecasts Bladder Cancer Recurrence
A multi-institutional study published in European Urology introduces a novel urine-based tumor DNA assay to predict recurrence risk in bladder cancer patients undergoing atezolizumab...