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Market and Industry Developments in Biotech and Healthcare
The biotech sector reflects mixed trends: Sage Therapeutics plans massive layoffs following its acquisition by Supernus Pharmaceuticals amid pipeline challenges. Major venture capital disputes...
AbbVie’s $2.1B Bet on In Vivo CAR-T Platform Signals Immunotherapy Push
AbbVie has agreed to acquire Capstan Therapeutics in a deal valued up to $2.1 billion, advancing the pharma giant’s in vivo CAR-T therapy ambitions. Capstan’s technology enables direct engineering...
Moderna’s mRNA Flu Vaccine Surpasses Competitor in Large Phase 3 Trial
Moderna’s seasonal influenza vaccine candidate, mRNA-1010, demonstrated a 26.6% relative vaccine efficacy over a licensed standard-dose seasonal influenza vaccine in adults aged 50 and older...
Sage Therapeutics to Slash Workforce After Supernus Acquisition
Sage Therapeutics, soon to be acquired by Supernus Pharmaceuticals, plans to lay off approximately 338 employees, representing the vast majority of its workforce. This decision follows Supernus’s...
AI Advances Early Detection and Prognosis in Pancreatic Cancer
Researchers at the University of Sharjah have developed novel artificial intelligence models capable of early-stage pancreatic cancer detection as well as disease prognosis prediction. Given...
Novel Gene Editing Control with Near-Infrared Activated CRISPR System
Researchers have engineered a chemically induced CRISPR system activated by near-infrared light, enabling precise spatiotemporal genome editing control. This platform expands upon the specificity...
Breakthrough Study Links Gut Microbiota to Miscarriage Risk in PCOS
At the 41st Annual Meeting of the European Society of Human Reproduction and Embryology, investigators revealed associations between altered gut microbiota and amino acid metabolism with increased...
Thermo Fisher-Tufts Study Shows CRO-CDMO Integration Cuts Cancer Drug Timelines
A white paper by Tufts Center for the Study of Drug Development, commissioned by Thermo Fisher Scientific, highlights that integrated contract development and manufacturing organization (CDMO) and...
Groundbreaking Luminescent Sensor Developed for Early Liver Cancer Detection
Scientists at the Indian Institute of Science have introduced a terbium-based paper sensor that exhibits high sensitivity for detecting the liver cancer biomarker β-glucuronidase. The novel...
Alzheimer’s Research Investment Surges After New Monoclonal Antibody Approvals
Following the FDA approvals of monoclonal antibodies Leqembi and Kisunla, investment and M&A deals in Alzheimer’s research soared by 780% from $2 billion in 2022 to $18 billion in 2024, according...
Breakthrough Links Genetic Ancestry to Dengue Severity via Skin Immune Responses
A collaborative study from the University of Pittsburgh and Brazilian institutes has for the first time demonstrated that genetic ancestry significantly influences inflammatory responses in human...
Moderna’s mRNA Flu Vaccine Beats Competitor in Phase 3 Trial
Moderna has reported positive phase 3 clinical trial results for its seasonal influenza vaccine mRNA-1010, demonstrating a 26.6% relative vaccine efficacy over a licensed standard-dose vaccine in...
AbbVie Acquires Capstan Therapeutics for $2.1 Billion to Boost CAR-T Pipeline
AbbVie is expanding its immunology and inflammation portfolio by acquiring Capstan Therapeutics for up to $2.1 billion. Capstan, a startup developing in vivo CAR-T therapies for autoimmune...
Early Detection Breakthroughs in Cancer and Disease Using AI and Biomarkers
Groundbreaking AI-driven diagnostic methods are emerging in oncology and disease management. The University of Sharjah developed AI models for early pancreatic cancer detection and prognosis...
New Insights into Post-Treatment Lyme Disease Syndrome and Persistent Bacterial Fragments
Research from Northwestern University revealed that fragments of Borrelia burgdorferi bacterial cell walls persist in the liver, disrupting protein expression and elevating liver dysfunction...
Sage Therapeutics to Lay Off Majority of Workforce Following Acquisition by Supernus
Sage Therapeutics announced plans to lay off approximately 338 employees, representing most of its workforce, after Maryland-based Supernus Pharmaceuticals' acquisition of the company. This...
Bioprocessing and Biomanufacturing Infrastructure Expands to Accelerate Biotech Innovation
Several advancements in bioprocessing infrastructure are highlighted, including the opening of the University of Oklahoma’s state-of-the-art bioprocessing core facility designed to support...
Genomic and Epigenetic Discoveries Illuminate Disease Mechanisms and Risk Factors
Cutting-edge studies shed light on genetic and epigenetic contributions to disease. Researchers linked genetic ancestry to differential immune responses in dengue severity, demonstrating higher...
Alzheimer’s Disease Sparks Investment Surge Fueled by Monoclonal Antibody Approvals
Following the approval of monoclonal antibodies Leqembi and Kisunla, investment and mergers in Alzheimer's disease therapies surged by 780% from 2022 to 2024. This renewed momentum has prompted...
Breakthroughs in Sustainable Biomanufacturing and Synthetic Biology
Innovations in sustainability and synthetic biology include bacterial production of paracetamol from plastic waste by engineered E. coli, merging biochemical and chemical methods. Additionally,...