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Zag Bio launches with $80M to engineer thymus‑targeted tolerance medicines
Zag Bio emerged from stealth with $80 million in financing and a platform that aims to induce immune tolerance by delivering bifunctional antibodies to the thymus, the organ that produces...
Hemab raises $157M to pursue coagulation disorder pipeline – sutacimig pivotal next
Hemab Therapeutics closed a $157 million financing to advance a portfolio of programs addressing rare coagulation disorders, including plans to start a pivotal trial of sutacimig in Glanzmann...
BridgeBio to push for approval after positive limb‑girdle Phase 3 readout
BridgeBio reported an encouraging Phase 3 interim readout for ribitol in limb‑girdle muscular dystrophy type 2I/R9 and said it will meet with the FDA to discuss regulatory plans and potential...
Zenas’ obexelimab drives 95% cut in new MS lesions in mid‑stage trial
Zenas Biopharma reported MoonStone phase‑2 data showing obexelimab, a bifunctional monoclonal antibody, produced a 95% reduction in new gadolinium‑enhancing brain lesions at 12 weeks in relapsing...
GeneDx expands into general pediatrics as exome/genome testing surges
GeneDx announced a commercial push into the general pediatrics market, hiring sales teams and streamlining ordering to capture demand after the American Academy of Pediatrics recommended...
Novartis snaps up Avidity for RNA push: $12B deal bolsters neuromuscular pipeline
Novartis agreed to acquire Avidity Biosciences for about $12 billion, securing three late-stage antibody-oligonucleotide conjugate (AOC) programs targeting neuromuscular diseases and a delivery...
Intellia halts CRISPR trials after liver toxicity — Phase III enrollment paused
Intellia Therapeutics paused enrollment and dosing in two late‑stage clinical trials of its in vivo CRISPR candidate for transthyretin amyloidosis after a study volunteer was hospitalized with...
GSK pays up for Empirico siRNA: $85M upfront to target COPD inflammation
GSK licensed global rights to Empirico’s EMP‑012, an inhaled siRNA in Phase 1 for chronic obstructive pulmonary disease (COPD), paying $85 million upfront with up to ~$745 million in potential...
Lilly and Nvidia to build pharma supercomputer — AI‑first drug discovery drive
Eli Lilly announced a partnership with Nvidia to build what the companies describe as the most powerful supercomputer operated by a pharmaceutical company, intended to train large AI models for...
Zenas antibody cuts MS lesions by 95% in phase 2 MRI readout
Zenas Biopharma reported Phase 2 MoonStone trial results showing obexelimab, a bifunctional monoclonal antibody, reduced new gadolinium‑enhancing brain lesions by 95% over 12 weeks versus placebo...
Electra closes $183M to fund pivotal sHLH trial and expand I&I pipeline
Electra Therapeutics raised $183 million in an oversubscribed Series C to support a global pivotal program for ELA026, its monoclonal antibody targeting SIRP receptors for secondary hemophagocytic...
Hemab raises $157M to scale coagulation disorder pipeline
Hemab Therapeutics closed a $157 million financing to advance multiple programs for bleeding disorders, including a pivotal trial planned for sutacimig in Glanzmann thrombasthenia and an...
GeneDx doubles down on pediatrics: revenue surge and market expansion plan
GeneDx reported Q3 revenue up 52% year‑over‑year, driven by exome and genome test growth, and announced a commercial build‑out targeting the general pediatrics market. The company plans to nearly...
Verily embeds Nvidia GPUs into Pre platform — omics and AI workflows accelerated
Verily integrated Nvidia’s GPU‑accelerated libraries and Blackwell/Hopper GPUs into its Pre precision health research platform to speed genomic and multiomics analyses for researchers, including...
Co‑Diagnostics sells $7M offering, forms MENA JV to commercialize diagnostics
Co‑Diagnostics priced a $7 million direct offering to institutional investors to fund working capital and corporate purposes, and the company also established a joint venture with Arabian Eagle...
Novartis deal: $12B buy of Avidity expands RNA neuromuscular push
Novartis announced an agreement to acquire Avidity Biosciences for roughly $12 billion, adding three late-stage antibody‑oligonucleotide conjugate (AOC) programs aimed at neuromuscular diseases....
Intellia halts phase 3 CRISPR dosing — liver safety probe
Intellia Therapeutics paused enrollment and dosing in two late‑stage trials of its CRISPR candidate nex‑z after a study volunteer was hospitalized with severe liver injury. The company moved...
Takeda, Innovent ink $11.4B I‑O/ADC pact — $1.2B up front
Takeda Pharmaceutical agreed to codevelop and commercialize up to three immuno‑oncology (I‑O) and antibody‑drug conjugate (ADC) candidates from Innovent Biologics in a deal valued at up to $11.4...
BridgeBio posts phase‑3 win — prepares FDA meeting on LGMD drug
BridgeBio reported positive interim Phase 3 data for BBP‑418 in limb‑girdle muscular dystrophy type 2I/R9, meeting prespecified thresholds and prompting the company to seek discussions with the...
Zenas antibody slashes MS lesions — midstage readout impresses investors
Zenas Biopharma reported that obexelimab, a bifunctional monoclonal antibody, produced a 95% reduction in new gadolinium‑enhancing T1 brain lesions at 12 weeks in the Phase 2 MoonStone study in...