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Latest Biotech News

CDH17+ tight-junction cells: new drivers of colorectal liver metastases

January 05, 2026

A Nature Communications study identified a subpopulation of tight-junction–high, CDH17‑positive colorectal tumor cells as principal drivers of liver metastasis, reporting functional and molecular...

MIS‑C biomarkers... serum panel tracks severity and recovery

January 05, 2026

A Pediatric Research paper from Wolff and Koutroulis mapped serum immune biomarkers that correlate with disease severity and recovery trajectories in Multisystem Inflammatory Syndrome in Children...

Romosozumab edges PTH analogs in fracture prevention – study

January 05, 2026

A recent comparative study published in Biol Sex Differ reported that romosozumab outperformed parathyroid hormone (PTH 1–34) analogs in reducing osteoporotic fractures among women, finding...

AI in digital pathology: accuracy gains collide with deployment hurdles

January 05, 2026

A sector review on AI in digital pathology outlined recent innovations, validation challenges, and integration barriers that laboratories face when deploying machine‑learning tools for...

St. Jude unveils assay: finds off-target edits missed by others

January 04, 2026

St. Jude Children’s Research Hospital published a new assay that improves detection of small off-target edits produced by base editors. The team released the method to enable researchers and...

BEAVER trial: binimetinib–encorafenib show activity in non‑V600E BRAF tumors

January 04, 2026

The Phase II BEAVER trial reported clinical activity for the MEK inhibitor binimetinib combined with the BRAF inhibitor encorafenib in advanced solid tumors harboring non‑V600E BRAF alterations....

Insilico surges after Hong Kong listing: finance report

January 04, 2026

BioCentury’s finance roundup reports a significant market gain for Insilico following its Hong Kong listing. The coverage details the capital infusion and market valuation shifts that followed the...

Harmeier returns to lead Roche venture fund — BioCentury report

January 04, 2026

BioCentury reports that Harmeier has returned to lead the Roche venture fund, a management move that revises leadership at one of Big Pharma’s principal corporate venture arms. The write‑up lists...

Mapping MASH: liquid biopsy partnership launched

January 04, 2026

Hepta and collaborators announced a liquid biopsy technology and a landmark partnership to map the biology of metabolic dysfunction‑associated steatohepatitis (MASH). Hamed Amini described a...

Engineered co‑signaling receptors: reduce T‑cell off‑target reactivity

January 04, 2026

A study led by Cabezas‑Caballero and colleagues reports engineered co‑signaling receptors that improve T cell precision by limiting off‑target activation. The team demonstrated that redesigned...

Phase 1/2: autologous CD133+ stem cells tested for Asherman

January 04, 2026

Researchers reported a Phase 1/2 trial testing autologous CD133+ bone marrow‑derived stem cells for Asherman syndrome, a fibrotic uterine condition. The trial evaluated feasibility, safety and...

Live tumor‑fragment platform: predicts immunotherapy ex vivo

January 04, 2026

A team introduced a live tumor‑fragment platform that preserves tumor architecture to assess immunotherapy responses ex vivo. The system allows drug exposure and readout of immune‑mediated tumor...

Fluorescent D‑amino acids track Lactobacillus in vivo: live probiotic imaging

January 04, 2026

Researchers Wei, Liu and Zhou developed a fluorescent D‑amino acid labeling method to track Lactobacillus strains in vivo, enabling direct imaging of probiotic colonization and persistence. The...

Serum biomarkers map MIS‑C severity — pediatric study

January 04, 2026

A Pediatric Research study by Wolff and Koutroulis identified serum immune biomarkers that track severity and recovery in Multisystem Inflammatory Syndrome in Children (MIS‑C). The paper...

AbbVie pays $1.1B for Zelgen T‑cell engager – gains ex‑China rights

January 04, 2026

AbbVie struck a $1.1 billion deal to acquire ex‑China rights to Zelgen Biopharmaceuticals’ lead oncology asset, alveltamig (ZG‑006), a trispecific T‑cell engager targeting DLL3. The agreement...

Insilico jumps after Hong Kong listing: finance report

January 04, 2026

Insilico Medicine saw a sharp market move following its Hong Kong listing, according to a BioCentury finance report. The biotech’s public debut delivered a material valuation uplift that traders...

Harmeier returns to lead Roche venture fund: management shake‑up

January 04, 2026

Roche announced the return of Harmeier to head its venture fund, signaling a leadership reset at its corporate venture arm. BioCentury reported the management move on Jan. 2, 2026, as part of a...

Third CRL sinks Outlook’s ONS‑5010 – shares tumble

January 04, 2026

Outlook Therapeutics received a third complete response letter (CRL) from the U.S. FDA for ONS‑5010, its bevacizumab biosimilar formulation for wet age‑related macular degeneration, prompting a...

DEA extends telemedicine prescribing flexibilities through 2026 – advocates urge permanence

January 04, 2026

The U.S. Drug Enforcement Administration extended temporary telemedicine prescribing flexibilities for controlled substances through the end of 2026, according to MedCity News. The fourth...

Psithera exits Roivant with $47.5M Series A – targets immune, inflammatory programs

January 04, 2026

Psithera Inc. completed a spin‑out from Roivant and closed a $47.5 million Series A financing while appointing Eric Shaff as president and CEO, the company disclosed in late 2025. The new entity...