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Sarepta’s Duchenne Gene Therapy: Safety Concerns Mount
Sarepta Therapeutics faces heightened scrutiny following a second death due to acute liver failure associated with its gene therapy Elevidys, approved for Duchenne muscular dystrophy. Both...
AI and Drug Discovery: Insilico Medicine’s Pan-KRAS Inhibitors
Insilico Medicine has announced the discovery of novel pan-KRAS inhibitors through its AI-powered generative platform Chemistry42. Combining structure-based drug design and scaffold hopping, the...
Immunotherapy Advances in Pancreatic and Liver Cancer
Recent studies report remarkable immunotherapy responses in subsets of pancreatic cancer patients treated solely with immune checkpoint inhibitors, exhibiting unprecedented progression-free...
AI Innovations Fueling Biotech R&D and Diagnostics
Multiple AI-driven initiatives are reshaping biotech research and diagnostics. Xaira Therapeutics has released an expansive Perturb-seq dataset to accelerate virtual cell modeling and AI drug...
AI Labs Expand U.S. Presence Amid Drug Discovery Push
Isomorphic Labs, an Alphabet-backed AI drug discovery company, has hired its first U.S.-based chief medical officer and established an office in Cambridge to facilitate clinical advancement of...
FDA Launches New Priority Review Voucher Program
The U.S. Food and Drug Administration unveiled a pilot priority review voucher program aiming to accelerate drug review times from up to a year down to as little as one month for treatments...
Cancer Biomarker and Imaging Research Accelerates with AI
Researchers have unveiled new AI-driven computational tools transforming biomarker discovery and medical imaging analysis. The recently published moPepGen platform enhances detection of diverse...
Advances in Sustainable and Circular Bioeconomy Strategies
A policy report highlights pathways for sustainable and circular aquaculture development in Germany and Brazil, emphasizing the potent yet underutilized freshwater aquaculture sectors. Separately,...
Neonatal Care Innovations: Training and Automated Monitoring
New educational programs using simulation-based training improve neonatal endotracheal intubation skills among clinicians, enhancing patient safety in critical care units. Complementing this,...
Lilly's $1.3 Billion Verve Therapeutics Acquisition Shakes Cardiovascular Gene Editing
Eli Lilly agreed to acquire Verve Therapeutics for up to $1.3 billion, marking a strategic move to expand its cardiovascular gene editing portfolio. Verve's lead program, VERVE-102, targets PCSK9...
Sarepta's Elevidys Gene Therapy Halted After Second Acute Liver Failure Death
Sarepta Therapeutics halted shipments of its DMD gene therapy Elevidys to non-ambulatory patients following a second fatal case of acute liver failure. Both deaths occurred in adolescent boys with...
Supernus Pharmaceuticals Acquires Sage Therapeutics for Up to $795 Million
Supernus Pharmaceuticals agreed to acquire Sage Therapeutics at an initial valuation of approximately $561 million, with additional contingent payments potentially increasing the deal value to...
FDA Introduces Accelerated Review Voucher Program Amid Workforce Strains
The U.S. Food and Drug Administration launched a new priority review voucher program intended to incentivize drug developers addressing national health priorities by offering accelerated review...
AI and Machine Learning Propel Breakthroughs in Drug Discovery and Diagnostics
Advances in artificial intelligence and machine learning are reshaping biotech, enabling novel protein design, diagnostic testing outside labs, and improved biomarker discovery. The AI-driven...
Emerging Dual Immunotherapy Extends Liver Cancer Patient Survival and Gains Global Approvals
Researchers at the University of Hong Kong pioneered a dual immunotherapy combining PD-1 inhibitor nivolumab and CTLA-4 blocker ipilimumab to treat advanced hepatocellular carcinoma. This...
Novel AI Application Boosts Public Health Campaigns Against HIV
Researchers led by Dolores Albarracin have deployed AI methods to classify and optimize public health messaging for HIV prevention targeting men who have sex with men (MSM). By analyzing a large...
Nanoneedle Patch Offers Painless, Repetitive Tissue Sampling for Disease Monitoring
Scientists at King’s College London developed a nanoneedle patch embedded with tens of millions of microscopic needles that collect molecular data from living tissues without causing pain or...
Single-Cell and Imaging Technologies Unlock Disease Mechanisms in Cancer and Autoimmunity
Cutting-edge single-cell RNA sequencing and multiplexed imaging advances deepen insights into complex diseases, including breast cancer heterogeneity and autoimmune disorders. Novel quantitative...
Significant Biopharma Deals Highlight Accelerating Investment in AI-Driven Drug Development
Biopharma deal-making remains brisk in 2025, with notable transactions including BioNTech's $1.25 billion acquisition of CureVac to advance mRNA oncology programs, Astrazeneca's $5.3 billion...
Sarepta Suspends Duchenne Gene Therapy After Second Liver Failure Death
Sarepta Therapeutics has temporarily halted shipments of its gene therapy Elevidys for non-ambulatory Duchenne muscular dystrophy (DMD) patients following a second death caused by acute liver...