A new data portal by AtlasXomics hosts spatial epigenomics datasets generated via Deterministic Barcoding in Tissue sequencing (DBiT-seq), enabling researchers to explore gene regulation in native spatial contexts. The portal includes data from Alzheimer’s disease, gastric adenocarcinoma, and developmental studies, incorporating chromatin accessibility and histone modification maps in tissues. These resources provide critical insight into tumor heterogeneity and gene regulatory architecture, supporting advances in biology and disease research with spatially-resolved epigenomic data.