Two independent studies exposed converging mechanisms implicated in Parkinson’s disease. A multi‑omics analysis linked cuproptosis‑related genes to PD pathogenesis, identifying copper‑dependent cell‑death pathways associated with disease signatures. In parallel, work in npj Parkinson’s Disease implicated low‑affinity Fc gamma receptors on microglia in driving dopaminergic neuron loss. Authors said the findings open targets for modulating microglial responses and metal‑dependent cell‑death pathways; both studies used human tissue datasets and animal models. Cuproptosis refers to a recently described copper‑dependent form of regulated cell death, distinct from apoptosis and necroptosis, that may be actionable in neurodegeneration.