Emerging biomarkers and diagnostic platforms are reshaping clinical assessment and disease monitoring. The Pediatric Weight Questionnaire offers a standardized tool for evaluating childhood obesity challenges. Chitinase-3-like Protein 1 (CHI3L1) emerges as a promising biomarker for liver disease diagnosis and management. Viome and Scripps Research collaborate to validate a stool-based colorectal polyp test leveraging RNA sequencing and AI for early cancer detection. These innovations enhance precision in identification and intervention across diverse health conditions.