An international consortium published NeuMap in Nature, presenting a single‑cell transcriptional atlas that maps neutrophil states across tissues and disease conditions and identifies functional hubs relevant to infection, inflammation and cancer. The resource synthesizes over a million cells and offers trajectories that may guide therapeutic targeting of neutrophil subpopulations. Separately, Yale researchers described an EHR‑embedding‑enhanced polygenic risk score (EEPRS) in the American Journal of Human Genetics, showing improved PRS performance by incorporating electronic health record phenotypic embeddings. Both efforts underscore how large‑scale profiling and EHR integration are being used to refine predictive models and identify actionable biology; NeuMap is a reference atlas, while EEPRS embeds clinical context into genetic risk.
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