Germany’s DZNE launched NeuroGenomeHub, a brain genomics initiative funded with about €6 million to build a global genome database for neurodegenerative diseases. DZNE said the project will sequence samples from roughly 25,000 individuals over the next two years, including data drawn from blood and other specimen types collected in ongoing DZNE studies. The initiative will leverage sequencing technologies such as long-read platforms and include DNA methylation analysis to enrich the database. DZNE said it will draw on resources including the Rhineland study in Bonn, which focuses on genetic underpinnings of healthy aging and dementia prevention. DZNE’s scientific director Joachim Schultze said the database is designed to identify genome-linked features that influence disease risk and progression, aiming to support future diagnostics, prevention strategies and therapies.
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