Technological innovations are fundamentally altering neurological and psychiatric treatment landscapes. A novel mobile app, OTX-202, delivers suicide-focused cognitive-behavioral therapy, significantly reducing suicidal behaviors in high-risk psychiatric inpatients. Deep learning models like DeepISLES improve the clinical accuracy of ischemic stroke lesion segmentation, enabling better patient management. Additionally, advances in understanding macrophage immune regulation via CRISPR and machine learning shed light on innate immunity dynamics, informing neuroinflammatory conditions. These developments open new pathways for digital and computational therapies in neuropsychiatric care.