The Allen Institute is launching a $200 million effort, the Brain Health Accelerator, aimed at translating brain atlas-scale understanding into medicines for neurodegenerative diseases. The initiative is designed to build “ground truth” disease characterization at scale by integrating technologies spanning transcriptomics, proteomics, neuroimaging, and AI. The program also includes expanded tissue coordination to support large, harmonized collections across sites. Dirk Keene, currently associated with UC San Diego’s tissue coordinating center plans, will anchor a west-coast network following a prior role facilitating brain tissue donation collaborations with the Allen Institute. Allen Institute said the initiative is intended to speed modeling and therapeutic development by unifying data generation and analysis methods across participating institutions, rather than relying on smaller, fragmented datasets typical of single-site programs.