Emerging pediatric research addresses early disease detection, health care delivery, and novel assessment tools. A personalized liquid biopsy assay enables sensitive detection and monitoring of pediatric CNS tumors. The Pediatric Weight Questionnaire (PWQ™) is developed as an obesity assessment tool tailored for children and adolescents. Additionally, studies on healthcare costs linked to COVID-19 in pediatric populations and delirium detection tools in long-term care provide data for optimizing pediatric health systems.