A recent study has demonstrated that incorporating nanoparticles into intracortical microelectrodes significantly boosts their recording longevity and stability by attenuating the brain’s foreign body response. This advance addresses longstanding challenges in brain-machine interfaces, which require consistent neural signal capture over extended periods. Researchers combined nanomaterials engineering with neurobiology to develop microelectrodes that maintain functionality, enabling improved interfaces for neuroprosthetics and neurological disorder therapies.