Scientists at King’s College London have unveiled a nanoneedle patch containing tens of millions of microscopic needles capable of sampling molecular data from tissues without pain or damage. This innovation offers a minimally invasive alternative to traditional biopsies, enabling frequent, longitudinal monitoring of cancer and neurodegenerative diseases. By extracting detailed molecular fingerprints such as proteins and mRNA, the device allows real-time insights into disease progression at the cellular level, potentially revolutionizing diagnostics and patient management.