Scientists at King’s College London have created a nanoneedle patch comprising millions of microscopic needles that collect molecular information from living tissues without pain or damage. This advancement, detailed in Nature Nanotechnology, promises to revolutionize biopsies by allowing real-time, longitudinal monitoring of disease such as cancer and neurodegenerative disorders. The minimally invasive device can capture spatial and temporal molecular data, facilitating detailed diagnostics and treatment tracking inaccessible through traditional, destructive biopsy methods.