Researchers described nanoliposome formulations that potentiate conventional antibiotics against multidrug‑resistant Salmonella enterica serovar Typhimurium, restoring bactericidal activity in preclinical models. The study demonstrated that lipid‑based carriers can enhance antibiotic uptake or disrupt resistance mechanisms, improving clearance in vitro and in infection models. The approach offers a translational path to extend the lifespan of existing antibiotics by combining them with nanoformulations rather than relying solely on new chemical entities. Authors suggest the technology could be deployed rapidly as an adjunct to existing drugs, with potential near‑term applications in severe MDR enteric infections where few alternatives exist.