GenomOncology will integrate Pacific Biosciences’ HiFi whole-genome sequencing secondary analysis pipeline into its Pathology Workbench reporting platform. The goal is to translate long-read WGS output into clinician-ready reports with structured variant interpretation, evidence curation, and report generation. Cleveland-based GenomOncology said the combined workflow will unite PacBio research-use-only secondary analysis—aligned reads and variant calls—with Pathology Workbench’s tertiary steps, including quality control review and clinical context handling. The company framed the move as a practical solution to an operational bottleneck in getting long-read results into routine lab reporting. An initial focus will include tumor types and reporting programs tailored for specific clinical use cases, including myeloid-focused panels and potential reimbursement requirements. For molecular diagnostics teams, the workflow integration could reduce manual transformation steps and standardize how long-read WGS findings are packaged for ordering clinicians.