Researchers in the United Kingdom have reported the birth of eight healthy children using mitochondrial donation techniques designed to prevent the transmission of mitochondrial DNA diseases. The process involves transferring nuclear genetic material from a fertilized egg of a carrier mother to a donor egg with healthy mitochondria. This IVF-based approach, legalized in the UK since 2015, provides hope for families at risk of debilitating mitochondrial disorders. All children to date are developing normally, and ongoing studies aim to expand clinical understanding and inform broader adoption of this reproductive technology.