A series of recent studies document successful births of children generated through three-person IVF techniques involving mitochondrial donation. These procedures transplant nuclear DNA from affected mothers' fertilized eggs into donor eggs with healthy mitochondria, significantly reducing risks of mitochondrial DNA-related diseases. The results, supported by multiple UK teams and published in top journals, highlight promising outcomes in preventing inherited mitochondrial disorders. The approach remains highly regulated and controversial but offers a seminal advancement in reproductive medicine for patients at genetic risk.