The Machine Intelligence from Cortical Networks (MICrONS) initiative has delivered the most comprehensive wiring diagram of a mammalian brain, integrating anatomical data with functional neuronal activity for hundreds of thousands of cells. This pioneering work, led by neuroscientists including Clay Reid at the Allen Institute, combined cutting-edge imaging and AI technologies to decode neuronal connectivity patterns. The resource advances understanding of how neurons coordinate responses to stimuli and provides a foundational dataset for both neuroscience and artificial intelligence research.