Researchers reported GARC, a gelatin-assisted recombinase polymerase amplification and CRISPR/Cas12a tandem assay, designed to detect Listeria monocytogenes with high sensitivity and a visually interpretable workflow. The assay uses temperature-responsive gelatin to physically separate amplification and CRISPR components during isothermal incubation, aiming to improve performance over one-pot designs. In analytical testing, the optimized platform achieved a detection limit down to 10 ag/µL for an hlyA target and successfully detected low inoculum levels in salmon matrices after a seven-hour enrichment step. The approach is positioned as a practical option for food-safety surveillance where speed, reagent stability, and workflow simplicity are critical.