Researchers at Chuo University have pioneered a microfluidics-based methodology for the high-throughput fabrication of artificial cells containing model DNA condensates mimicking eukaryotic nuclei. This technology generates uniform lipid bilayer vesicles (giant unilamellar vesicles) embedding intricately structured DNA nanostars, assembled under osmotic pressure. The system facilitates protein synthesis within these model nuclei, marking a significant advancement towards creating synthetic cell systems capable of complex biological functions akin to living organisms.