A Bayesian network meta-analysis of six randomized trials involving 2,599 patients with acute brain injury found that a transfusion threshold of 9 g/dL ranked highest for functional outcome. The analysis suggested the more restrictive 7 g/dL trigger did not outperform 9 g/dL and reported no clear increases in adverse events. The findings add quantitative support to transfusion-threshold debates that are often driven by local protocols. For clinicians managing neurological injury, the data points toward a threshold balance that could shape transfusion practice in intensive care settings.
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