Vanderbilt researchers built a reusable electronic health record pipeline that converts minute-by-minute ICU arterial blood pressure streams into research-ready longitudinal profiles. The approach cleans and imputes high-frequency data into stable trajectories designed for perioperative research. The pipeline is aimed at reducing friction for studies that rely on granular physiologic signals, where missingness and inconsistent documentation can undermine comparability across patients and sites. For translational and clinical research teams, the work offers a standardized way to retain physiologic detail while controlling data quality risk.