Jazz Pharmaceuticals appointed current COO Renée Galá as incoming CEO, succeeding co-founder Bruce Cozadd effective August 2025, signaling continuity amid operational shifts. Karyopharm Therapeutics implemented a 20% workforce reduction as it pursues strategic alternatives and financing amidst ongoing challenges. Additionally, Pfizer's longtime communications chief Sally Susman announced departure, marking a notable leadership transition. Executive appointments also include multiple senior roles at QuidelOrtho and Becton Dickinson, reflecting organizational restructures responding to evolving business and innovation demands in the biotech and med-tech sectors.