Recent studies reveal advancements in cancer immunotherapy and diagnostics. Researchers engineered gut bacteria to boost colorectal cancer patient survival, while new antibody-cytokine fusion proteins enhance antitumor immunity by overcoming regulatory T-cell suppression. Dana-Farber introduced MARLIN, an AI-based DNA methylation classifier markedly improving acute leukemia subtype detection. Additionally, a PET tracer targeting nectin-4 enables rapid imaging of aggressive triple-negative breast and urothelial cancers, promising improved clinical management.