Researchers reported durable HIV remission following a heterozygous CCR5Δ32 stem-cell transplant, marking a notable advance in curative research. Case details indicate the transplant conferred prolonged viral control without antiretroviral therapy, challenging prior assumptions that homozygous CCR5Δ32 status is required for cure-like outcomes. Published reports and commentary place the finding alongside other remission cases and stem-cell interventions, underscoring the rarity but scientific importance of these outcomes. The paper details immune reconstitution, viral reservoir measures, and clinical follow-up that together support sustained remission. The case renews interest in stem-cell and gene-editing strategies targeting CCR5 and reservoir-clearing approaches; sponsors and academic centers are likely to reassess combination strategies that could replicate remission safely at scale.
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