The Global Neurodegeneration Proteomics Consortium (GNPC) published extensive analyses from the largest proteomic dataset to date, encompassing 250 million protein measurements from over 35,000 biofluid samples worldwide. Their studies revealed protein biomarkers and molecular pathways linked to Alzheimer's, Parkinson's, frontotemporal dementia, and ALS. The freely accessible dataset and accompanying publications in Nature Medicine and Nature Aging offer valuable resources for early diagnosis and development of targeted therapies. Bill Gates praised the consortium as a model of international scientific collaboration.