Researchers at Harvard University led by George Church have developed a stem cell differentiation method that induces meiosis, progressing toward the generation of human eggs in a dish. This breakthrough bypasses the traditional primordial germ cell state, enabling meiosis initiation in vitro, addressing a major infertility research hurdle. The method offers promising applications in drug development and future fertility treatments, where the availability of healthy gametes remains challenging. Church’s work represents a major step toward reproductive biology innovation and potential therapies for infertility.