San Diego‑based Genyro licensed Sidewinder, a DNA assembly technology from Caltech, to support large‑scale, high‑accuracy DNA synthesis for programmable biology. Genyro’s CEO Adrian Woolfson framed Sidewinder as enabling long, high‑fidelity constructs with a misconnection rate reportedly 10,000‑fold better than prevailing approaches, according to company commentary and the Nature publication that describes the method. The license pairs AI‑driven genome design with a physical DNA assembly platform to shorten the path from in‑silico designs to buildable sequences. Genyro said the capability reduces dependency on extensive clonal screenings and should accelerate applications across therapeutics, biomaterials, and industrial bioengineering while highlighting the need for robust safety screening in sequence design workflows.