The German Center for Neurodegenerative Diseases (DZNE) launched NeuroGenomeHub, a brain genomics initiative backed by approximately €6 million. The program aims to build a global genome database by sequencing samples from about 25,000 individuals over the next two years. DZNE plans to use blood and other sample types drawn from existing studies, including the Rhineland study in Bonn focused on healthy aging. The database will incorporate long-read sequencing and DNA methylation analysis to enrich genetic and epigenetic signals. DZNE’s scientific director Joachim Schultze said the effort is intended to identify genome features influencing disease risk and progression, supporting future diagnostics, prevention, and therapy development.