MeiraGTx agreed to buy back a failed eye gene therapy from Johnson & Johnson for $25 million upfront, following the therapy’s Phase 3 setback in X-linked retinitis pigmentosa. The transaction returns rights for bota-vec (botaretigene sparoparvovec) to MeiraGTx as the company pursues next steps for the asset. The deal reflects how gene therapy economics can shift quickly after late-stage disappointments, with companies re-optimizing cost structures and ownership to regain strategic flexibility. MeiraGTx’s move also coincides with additional financing activity across the gene therapy space, signaling continued investor interest despite trial volatility.
Get the Daily Brief